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A placenta-specific enhancer found downstream of the CSH genes (291) as well as pituitary-specific repressor sequences found upstream of GH2, CSH-1 and -2, and CSHL-1 may serve to limit transcription of these particular genes to the placenta (292)

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Like any medication, it may take a few weeks to adjust to side effects, and your doctor may need to adjust the dose over a period of time to figure out the correct dose