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Cytokine storm or CRS, a clinical state of hyper-inflammation, is a prominent feature of COVID-19 severity, linked to respiratory dysfunction, ARDS with adverse disease outcomes 220,221

There are wide areas of this field still to be explored, including epigenetic regulation of immune cell metabolism and inflammation 45 , post-translational modifications utilizing metabolites 109,110,111 , and the discovery of as yet unknown immunometabolic signaling pathways

Analyses were adjusted for age, sex, BMI, Townsend index, energy, alcohol, and carbohydrate intake

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Subsequently, the GSH/GSSG ratio in RG2 (Fig

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