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1, July 2005, pp

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Non-protein-coding regions There are nearly 25% of mtDNA mutations occurring in non-protein-coding regions including tRNAs and the highly conserved ribosomal RNA [125]

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6.4 Oxidative stress and diabetic vascular complications OS plays a central role in the pathogenesis of diabetic vascular complications through multiple interconnected pathways that promote endothelial dysfunction, vascular inflammation, and extracellular matrix remodeling