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Science 2005;308:1587-1589 Prentice A, Deary AJ, Goldbeck-Wood S, et al

Hypotensive and endothelium-independent vasorelaxant effects of methanolic extract from Curcuma longa L

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Science 319 , 202206 (2008)

For these solutes to induce blood-to-bile water transport primarily, they need to be concentrated and retained into a confined space (the bile canaliculus)

For example, aloin A (AA), an antherone compound, significantly protected against DSS-induced colitis by alleviating inflammatory symptoms, reducing the inflammatory response, preventing colon shortening and apoptosis, and promoting cell proliferation