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In the context of IgG-mediated autoimmune diseases, FcRn maintains high levels of pathogenic auto-Abs in the circulation and tissues via a cellular recycling process that extends the plasma half-life of IgG Abs

PAIN 1996;68:37583

ASO titers were ordered to check for post-streptococcal arthritis which were normal

Further research, especially randomized controlled trials, is essential to clarify these relationships, focusing on optimal dosages and the timing of supplementation post-diagnosis

Moreover, a high percentage (almost 30%) of these patients exhibit idiopathic anemia (77) that may be caused by blood loss due to repetitive blood tests and surgical interventions, as well as occult bleeding (mainly in the gastrointestinal tract) during hospitalization

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