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Due to the decreased expression of tight junction proteins, they have a more permeable blood-brain barrier (BBB)

Numerous studies have demonstrated that HO-1 has a significant effect on diabetic complications, with induction of HO-1 protein expression enhancing antioxidant defense and reducing inflammatory factors (Table 2)

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With one or two sessions per year, many patients report lasting improvements without the need for constant re-administration

Clonis, Y.D

[15] In hepatocytes, compounds undergo enzymatic transformation in two main phases: Phase I reactions (often mediated by cytochrome P450 enzymes) introduce functional groups, and Phase II reactions conjugate these compounds to increase water solubility and facilitate elimination