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[18] (Read more about this in my article on iodine and Hashimotos .) Selenium has a narrow therapeutic index, and doses of under 100 mcg per day (when used as monotherapy) may not be sufficient for improving Hashimotos symptoms and markers, while doses in excess of 800 mcg per day can be toxic

doi: 10.1007/s11882-017-0725-y