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Pre-clinical findings from in vitro models indicate that ibuprofen prevents oxidative damage induced by LPS injection and better protects dopaminergic neurons against glutamate neurotoxicity than ASA (116, 117)

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This resulted in improved osmotic fragility, reduced phosphatidylserine positivity, amelioration of RBC cation content, reduction of Na/K/Cl cotransport and Na/H-exchange overactivation, and decrease in erythroid vesicles release in vitro

4 An estimated 1030% of adults have tinnitus, and the prevalence increases with age

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