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A follow-up study in 31 of these women found that taking 5 grams of collagen daily for a total of 4 years was associated with a progressive increase in BMD

This makes sense biologically

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Remarkably, gene expression profiling studies have shown that GHK-Cu treatment can shift aged fibroblasts toward more youthful gene expression patterns, reversing age-related changes in gene activity related to collagen production, matrix remodeling, inflammatory responses, and cellular senescence