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Animal handling and experimentation were carried out in accordance with the guidelines of the Guide for the Care and Use of Laboratory Animals and were approved by the Laboratory Animal Care and Use Committee of the Shaanxi University of Chinese Medicine

While some studies suggest very short-lived protection against infection but stable protection against severe outcomes, methodological flawssuch as inconsistent follow-up, selective exclusion, and case-counting window biasundermine claims of protection

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The work was supported by the Austrian Science Fund FWF The project was supported by the National Laboratories Programme, National Laboratory for Drug Research and Development (PharmaLab), RRF-2.3.1-21-2022-00015

The pharmacokinetic gap between peak tirzepatide effect and peak semaglutide effect creates a vulnerable window where appetite suppression decreases and weight regain risk increases

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