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Kidney pain is more likely to be severe, one-sided, and accompanied by other symptoms like fever, nausea, burning with urination, or blood in the urine

In contrast, serum ELISA antibody tests detect only immune sensitization, indirect evidence that cannot confirm current or ongoing exposure, and they lack validation for exposure assessment

doi: 10.1212/NXI.0000000000001125 97 SunCYuWZhaoZSongCLiuYJiaGet al

This article meets the Accreditation Council for Graduate Medical Education and the American Board of Medical Specialties Maintenance of Certification competencies for Patient Care and Medical Knowledge

We compared islet cell distributions and determined graded intensities of glutathione peroxidase1 (GPX1), a key enzymatic mediator involved in detoxifying hydrogen peroxide, by applying combined immunohistochemistry for GPX1, insulin and glucagon, in pancreatic sections from new-onset T1D (group 1), non-diabetic autoantibody-negative (group 2), non-diabetic autoantibody-positive (group 3) and long-term diabetic (group 4) donors