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[68] performed a multicenter study of 101 PEH repair with anterior gastropexy without fundoplication, showing an acceptable recurrence rate of 16.8% at 12-month follow-up and avoiding complications of mesh positioning and anti-reflux procedures

The rationale above is mechanism-based community reasoning, not direct combination evidence

The process involved addressing concerns and making adjustments as necessary, such as refining the PFS ratesetting methodology in consideration of interested party feedback

13 Other studies suggest that a few days use of red-light therapy can both shorten active lesion time and decrease recurrence, especially when used in conjunction with conventional topical treatments

Dose adjustments are made based on symptoms and sensitivity under a clinicians guidance

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