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doi: 10.1002/anie.202000451 281 TsangC

Claudins create charge-selective channels in the paracellular pathway between epithelial cells

Studies including serial liver biopsies during continued treatment

2019 Mar 1;22(3):247-52

With regard to heart rhythm abnormalities, and atrial fibrillation more specifically, preclinical research indicates there may be a link to vitamin D

As SnCE1 Y212A shows the strongest processing, its existence as monomer, as shown by analytical SEC, together with being non-acetylated, might account for the improved autoproteolytic processing compared to SnCE1 C256A and wild type SnCE1