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SKU: 65207630396
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The earliest study was a phase 3 REGARD trial (73) conducted in 2009, which involved 355 patients with GC or gastroesophageal junction adenocarcinoma who underwent first-line platinum- or fluoropyrimidine-containing chemotherapy

10.1016/j.neuint.2010.10.016 278 ZhangH.BaiL.HeJ.ZhongL.DuanX.OuyangL.et al (2017)

This inflammatory state can disrupt neurotransmitter systems, impair neuroplasticity, and contribute to structural and functional changes in key brain regions involved in mood regulation