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Additionally, IF stainings did not show any differences in subcellular localization of NUPR1 after CSE treatment (Fig

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Short-chain fatty acids (SCFAs), such as butyrate, epigenetically regulate drug transporter expression and suppress the SASP, while dietary interventions may create a microenvironment favorable to senolysis

Following its uptake, FOXO4-DRI reduced the number of senescence-induced FOXO4 foci, PML bodies and 53BP1 DNA-SCARS, while not affecting the number of small 53BP1 foci (Fig