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For instance, senescent M1 macrophages within atherosclerotic plaques release SASPs, increasing oxidative stress levels within plaques, leading to instability, rupture, and a heightened risk of AF (Vellasamy et al., 2022)

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GLP-1 therapies like semaglutide have strong RCT support for clinically meaningful weight loss

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Other studies have shown that oxidative damage to nerve cells, a hallmark of ALS, was related to neurodegeneration [42]