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H 2 S and pyruvate production with fluorescent probe detection Kinetic H 2 S production was measured using AzMC (Sigma #802409), which is a fluorogenic probe selectively reduced in the presence of H 2 S producing 7-amino-4-methylcoumarin 29 and detectable with excitation wavelength Exc 350 nm and emission wavelength Emi 445 nm

Its systemic benefits include deep detoxification (especially of the liver), fighting oxidative stress that causes premature aging, and significantly boosting the overall immune system and energy levels

All other co-authors contributed intellectually to the designing, editing, and proofreading of the manuscript

The association of circulating glutamine levels and depression is still controversial in clinical settings, as our previous meta-analysis reported decreased glutamine levels in MDD patients [22], while unaltered levels were reported in other meta-analyses [48, 49]

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In cancer, aberrant activation of the ERK1/2 pathway often results in enhanced cell proliferation and resistance to apoptosis (Zhang et al., 2020[149]