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J Biol Chem 269 : 2706627073 Avissar N, Finkelstein JN, Horowitz S, Willey JC, Coy E, Frampton MW, Watkins RH, Khullar P, Xu YL, Cohen HJ 1996 Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells

Aging Clin Exp Res 24(1):2127

Genetic variations (polymorphism) in P-450 metabolism should be considered when patients exhibit unusual sensitivity or resistance to drug effects at normal doses

In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation

Inspect for Changes: Look for signs of spoilage, such as: Color Changes: A change in color can indicate chemical breakdown

If patients develop skin-related toxicities, the nurse should grade the toxicity, provide appropriate supportive care interventions, and work as part of the team for management