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Such pre-clinical investigations on breast cancer brain metastasis can pave the way for the treatment of patients in the clinical setting

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For the hypoxic group, a timer-controlled aerator was utilized for intermittent oxygenation, maintaining dissolved oxygen at approximately 1 mg/L

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In addition, Shulman and colleagues reported that a HFD induced an increase in acetate production in the intestine of mice, and then the increased acetate level led to activation of the parasympathetic nervous system and promoted secretion of growth hormone-releasing peptide and glucose-stimulated insulin