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Description

OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes

Anyomi BK, Fosu K, Lamptey EL, et al

By blocking FcRn-mediated IgG rescue from lysosomal degradation, these agents lower circulating pathogenic IgG autoantibody titers without broadly suppressing immune cells [26]

The co-localization of Halo-Rac1 with EEA1 or Lamp1 progressively increased over time after EV addition in WT cells, but this increase was attenuated in CIP4 KO cells (Fig