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Our probe enabled the determination of GSH concentration in the whole cell and three other subcellular compartments, something that would have required four different probes or assays in the past

Ca2+ then activates protein kinase C, which in turn activates the IKK complex

Targeting the human gut microbiome with small-molecule inhibitors

In the clinical setting, 2-DG has thus far been evaluated only in early-phase trials focused on safety and dose escalation, either as monotherapy or in combination with chemotherapy or radiotherapy, including NCT00096707/NCT00196707, NCT00633087, and related studies, which enrolled patients with various advanced solid tumors or high-grade gliomas

Hyperacetylation in histones reflects a high metabolic state in PSCs, which leads to gene activation for the maintenance of pluripotency

The proteins responsible for chromosomal adhesion form a circular complex, comprising Smc1, Smc3, Mcd1, Scc1, and Rec8, which induces chromosome condensation (18)