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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Whitby JD

In this analysis, nebulized GLY improved lung function and health status in patients irrespective of comorbidity count, supporting the use of nebulized GLY among patients with COPD and comorbidities in clinical practice

While GABAergic drugs (e.g., baclofen, bumetanide, homotaurine) show promise in preclinical models for ameliorating ASD-like behaviors, clinical translation remains limited by inconsistent efficacy and safety profiles

Both reasons are valid but the approach, expectations, and oversight should differ accordingly

797 Even neonatal rat ventricular muscle cells with low sensitivity to GPX4 inhibition underwent ferroptosis in the presence of cysteine deprivation, suggesting that inhibition of GPX4 promotes ferroptosis of cardiomyocytes under metabolic stress, such as cysteine deprivation

Future perspective and clinical translation Overcoming current limitations Although cannabinoids hold significant promise in cancer therapy, several challenges must be overcome to enable their successful clinical application