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FRCs from the spleen or lymph nodes were isolated by enzymatic digestion as described previously 55

Glutamate-cysteine ligase protects cells from ferroptosis by decreasing glutamate levels, converting them to -glutamyl peptides, and boosting GSH production (36) ( Figure 1 )

Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression

Taken together, these results suggested that redox control pathways in subcellular compartments are separately and precisely controlled to meet the specific redox requirements in these distinct locations.

Hirsch FR, Varella-Garcia M, Bunn PA, Di Maria MV, Veve R, Bremnes RM, et al

Edge-site engineering of defective Fe-N 4 nanozymes with boosted catalase-like performance for retinal vasculopathies