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doi: 10.3389/fimmu.2020.02184, 6 AminM

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A Phase III study of zanubrutinib plus rituximab versus bendamustine plus rituximab in transplant-ineligible, untreated mantle cell lymphoma

Upon binding, ivermectin causes a prolonged phase of chloride ion influx, resulting in hyperpolarization, neuronal firing inhibition, paralysis, and ultimately, death of the parasite ( -aminobutyric acid (GABA)-gated chloride channel at higher concentrations, to further inhibit nervous system dysfunction in susceptible parasites (78)

Altogether, it is of high relevance to identify metabolic factors that potentially serve as prophylactic treatments for the general population to promote and maintain health during aging, in addition to developing accessible and interpretable biological aging clocks