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On the other hand, an elevated concentration of homocysteine, and its metabolites such as homocysteine thiolactone and N-homocysteinyllysine result in health problems and has been indicated as an independent risk factor for cardiovascular disease and accelerated atherosclerosis

doi:10.1016/j.clinthera.2024.03.002

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Chronic ethanol exposure can activate the extrinsic apoptotic pathway in addition to the mitochondrial pathway

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The link between inflammation and manifested disease is at present only correlative, and the cause of the inflammatory response can at this point not be determined with certainty