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Coelho I, Casare F, Pequito DC, Borghetti G, et al

In line with patient studies, cellular and mouse models of ALS also showed high levels of ROS, along with elevated oxidation of membrane phospholipids (HNE, MDA), DNA (8-OHdG), and proteins (protein carbonyl groups, 3-NT) [94, 109,110,111]

doi: 10.1158/1078-0432.CCR-16-1326 176 BryantKLStalneckerCAZeitouniDKlompJEPengSTikunovAPet al

Thus, changes in peripheral NGF levels may constitute a molecular signal to induce NGF and TrkA transcription in the striatum (CNS)

Fast and slow voltage-dependent dynamics of magnesium block in the NMDA receptor: the asymmetric trapping block model

Jalil, Luigi Gabrielli, Mara Paz Ocaranza, Paul MacNab, Rodrigo Fernndez, Bruno Grassi, Paulina Jofr, Hugo Verdejo, Monica Acevedo, Samuel Cordova, Luis Sanhueza, Douglas Greig International Journal of Molecular Sciences.2024