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Therapeutic strategies targeting MDSCs Metabolic targeting in MDSCs MDSCs display high metabolic reliance and undergo extensive metabolic reprogramming in the TME to adapt to harsh conditions, such as hypoxia, oxidative stress, and nutrient scarcity (6)

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Therefore, the C/D ratio is a simple but effective tool to identify patients at risk of an unfavorable outcome

This work was also supported by the National Natural Science Foundation of China for Young Scientists (81601253) and the Key R&D Program of Henan Province (202102310062) to L.F

Laser Treatments (e.g., Intense Pulsed Light): These procedures can temporarily cause redness or swelling but are generally safe when performed by a trained professional

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