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4b and Extended Data Fig

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One hundred microliter aliquot of tissue homogenate supernatant was first incubated with 50 L KOH (1 mol/L) at 37 C for 30 min to fully hydrolyze the combined carnitine, and 10 L HCl (1 mol/L) was then added to neutralize the solution (sample A)

the results show that the peptides of the invention are able to modulate the expression level of genes involved in innate immune response, respect to basal conditions in primary human epidermal keratinocytes isolated from adult skin and at the tested concentration

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