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In this potentially life-threatening disease, the intrinsic factor for the absorption of vitamin B12 in the stomach is completely absent, resulting in a severe long-term vitamin B12 deficiency with consequences for blood formation, neurological disorders and an inflamed tongue

RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB

If you are low in B12, you will feel weak and tired

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They interact with G-protein-coupled receptors, ion channels, or internal cellular machinery to exert diverse effects, including hormonal stimulation, angiogenesis, mitochondrial regulation, or immune modulation