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Diagnosis of HPII can be made based on plasma proline levels, as well as elevated urinary P5C levels, proline, hydroxyproline, and glycine, which serve as important markers

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Lowering this oxidative burden in the scalp could indirectly reduce stress on androgensensitive follicles and limit redoxdriven amplification of androgen pathways, even though it does not block hormones or 5alpha reductase in the same way as systemic drugs