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BPC-157 ist ein Pentadecapeptid (15 AA, Sequenz: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) mit der Summenformel C 62 H 98 N 16 O 22 und einem MW von 1419.53 g/mol (CAS: 137525-51-0)

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A prodrug nanoparticle synthesized by conjugating PD-L1Pep-2 with doxorubicin via cathepsin B-cleavable peptide linker (FRRG) inhibited tumor progression in the 4T1 mouse breast tumor model by inducing doxorubicin-mediated immunogenic cell death and blocking PD-L1 through PD-L1Pep-2 102

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