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the invention encompasses cations of Formula I, wherein: R 1 is C 1-4 alkyl R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN

This provides higher bioavailability

The total density of BrdU+ cells expressing neuronal phenotypic markers DCX and/or NeuN also did not differ between TAM and vehicle-injected mice (Fig

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5-Amino-1MQ is designed precisely for this phenotype