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Overexpression of miR-506 in cholangiocytes leads to multiple PBC-like features, including impaired cell proliferation and adhesion, sensitization to bile acid-induced apoptosis, impaired energy metabolism, PDC-E2 overexpression and mislocation into the plasma membrane, and immune activation

Although data showed that 70% of children from the same age group who received Pfizer-BioNTech or Moderna mRNA-1273 had completed their vaccination series, there is still a low coverage of COVID-19 vaccines in this age group, particularly in the rural area

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