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In addition, we observed broad chemical diversity in the noncovalent building blocks comprising the hit-compounds

Highly damaging free radicals are passed down like hot potatoes between antioxidants like vitamin C, vitamin E, and alpha-lipoic acid, and finally to glutathione, which quenches a diverse array of free radicals and recycles the other antioxidants

J.Vzquez-AnM

c , Melting temperatures of apo and covalent Ub-PA complexes of indicated USP30 constructs, indicating similar melting temperatures for constructs with or without the box 4-5 insertion and with or without mutation of the three hydrophobic residues shown in a , suggesting that the protein is similarly stable once purified

49 , W530W534 (2021)