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Results: Three latent classes were identified: inefficient sleep and short sleep duration (34.6%), good sleep (50.4%), and low sleep quality with long sleep duration (15.0%)

For arthritis specifically, semaglutide has evidence from the STEP-9 knee osteoarthritis trial and studies on rheumatoid arthritis joint outcomes, while tirzepatide has shown roughly a 33% reduction in hsCRP and an 18% reduction in IL-6 (key inflammation markers) in meta-analyses

There is insufficient safety data for either compound during pregnancy, and animal studies with GLP-1 agonists showed adverse fetal effects

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10.1111/cen.13828 [DOI] [PubMed] [Google Scholar] Gleicher N., Darmon S., Patrizio P., Barad D

[DOI] [PMC free article] [PubMed] [Google Scholar] 239.Okyere J, Aboagye RG, Ahinkorah BO, et al