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Smolinska S, et al

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Maybe instead, we can go about increasing the chances that DHT interacts with enzymes that turn it into other testosterone byproducts

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Like other toxic heavy metals, Cd is greatly concentrated in the upper levels of food chain (Rikans and Yamano, 2000) and kidney (Satarug, 2018), even our heart (Peters et al., 2010), including cardiac death and myocardial infarction ( It is universally acknowledged that oxidative stress is the major event induced by Cd poisoning (Liu et al., 2009)

Mechanistically, itaconate inhibits GILT, a thiol reductase crucial for processing disulfide-rich neoantigens, thus impairing effective antigen presentation in wild-type settings