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Huang and Pranata, 2020

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In hypercholesterolemic mice, deletion of Arg2 or inhibition of arginase with BEC improves endothelial function and reduces atherosclerosis (Ryoo et al., 2008)

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AsALG-6 is eliminated during Ascaris programmed DNA elimination 65,66,67

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doi: 10.1093/pcmedi/pbae021 133 AmrKSAbdelmawgoudHAliZYShehataSRaslanHM

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A post-hoc subgroup analysis of that trial suggested benefit of prasinezumab in subjects with faster progression [209] and a comparison of MDS-UPDRS progression during the 4-year open-label extension phase with historical controls showed divergent trajectories in favour of prasinezumab from year 2 of treatment onwards [210]

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