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445 Immunotherapeutic treatments have shown significant efficacy in TNBCs due to tumor immune infiltration, neoantigens caused by mutational burden and higher genomic instability, and high levels of immune markers such as PD-L1 and programmed cell death 1 (PD-1)

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This ultimately impairs IVD biomechanical properties, subsequently leading to structural alterations and development of discogenic LBP, as well as more severe sequelae, including disc herniation, spinal instability, and stenosis with serious neurological consequences (Roberts et al., 2006)

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Family Medicine Physician with 20+ years in Family Medicine focused on nutrition, wellness, and whole-person health

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Turning the tide on Alzheimers disease: modulation of -secretase

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Results: Of the 3676 (representing 5.3 million) US adults with CLD, 22% (95% CI: 2124%) reported experiencing social isolation and 9% (95% CI: 8-10%) reported experiencing psychological distress

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C., & Kang, I

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