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Gabapentin inhibits bortezomib-induced mechanical allodynia through supraspinal action in mice

Part of the literature was retrieved from the previous study (7)

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393,394,395 Common etiologies include infection, metabolic disorders, drugs or toxins, alcohol, genetic factors, and liver tumors

These structural modifications significantly reduce IGF-1s binding affinity to IGF-binding proteins (IGFBPs), increasing the availability of the active peptide during in-vitro experimentation