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In contrast, some others reported comparable serum homocysteine concentrations between patients with NAFLD and healthy controls 7,23

The use of proton pump inhibitors (PPIs) has been associated with an increased risk of vitamin B12 deficiency, particular in older adults and those on long-term PPI therapy. Nutrition Reviews Duration-Dependent Risk Assessment The risk of B12 deficiency from PPIs grows with time

Failure to do so will result in return of the anemia and in development of incapacitating and irreversible damage to the nerves of the spinal cord