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[1,2,12 ] NAC improves mental health Oxidative stress has been associated with a variety of psychiatric disorders including: Anxiety 1-2g NAC daily can help reduce subjective anxiety through glutathione activity [13 ] Depression 1g NAC daily can help depressive symptoms [13 ] Bipolar disorder 1g NAC twice daily with usual medication, lowered depressive symptoms but not mania [14 ] Schizophrenia 1g NAC twice daily helped with restlessness [6,15 ] Substance use disorder preliminary evidence suggest that NAC can potentially help with addiction behaviour [1,12 ] OCD (obsessive-compulsive disorders) NAC influences the amino acid glutamine