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For instance, the precise mechanisms of oxidative cell death initiation and propagation in CNS diseases are not fully elucidated, and the roles of ROS in interacting with cellular signaling pathways are not completely understood

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Similarly, the other two control nanoprobes, i.e., (1) ApoE-decorated ApoE-PDHD nanoprobe without GGT responsiveness and (2) GGT-responsive BEAGA-PDHD nanoprobe without ApoE decoration, were prepared using single polymer N 3 -PEG 3.4k -PDHD and BEAGA 2 -PEG 2k -PDHD, respectively

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Puerarin attenuates oxidative stress and ferroptosis via AMPK/PGC1/Nrf2 pathway after subarachnoid hemorrhage in rats

Instead of causing sharp spikes, it leads to a sustained, unnatural elevation of baseline GH levels