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After being told by another skin clinic that nothing could be done about my acne except going on Accutane, I went to The Clinic Skin Health for a second opinion

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Oxidative decarboxylation of 6-phosphogluconate, catalyzed by 6-phosphogluconate dehydrogenase, then yields the ketose sugar, ribulose 5-phosphate, plus 1 mole of CO 2 , and the second mole of NADPH