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As nitrates and nitrites in the human body undergo metabolic conversion into nitric oxide, higher levels can disrupt thyroid function

Heliyon 10(11):112

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Therefore, the EORS hypothesis of aging consists of the inability to respond to energy demands or stress that leads to stress-induced catastrophic initiation of cellular death pathways and brain function decline

As the primary organ responsible for steroid metabolism, the liver is particularly susceptible to the toxic effects of 17--alkylated oral anabolicandrogenic steroids, such as stanozolol and methyltestosterone (74)

A Randomized Trial of Induction Chemotherapy or No Induction Chemotherapy Followed by Preoperative Chemoradiation in Patients with Esophageal Cancer