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The injury involves a locally diffuse injury involving cortical contusion and diffuse subcortical neuronal injury, induced by a pendulum striking a piston at the end of a saline-filled cannula (Ma et al., 2019)

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One cannot know ahead of time where these anatomical variations are located

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Although BP-1-102 is a specific inhibitor of STAT3 activity, BP-1-102-mediated downregulation of NF-kB activation relies on the demonstration that STAT3 interacts with and sustains NF-kB activity

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