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the anti-EphA2 or EphA4 antibody of an ADC of the invention is conjugated to the cytotoxic agent via a linker, wherein the linker is cleavable at a pH of less than 5.5

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doi: 10.3390/toxins14020067 124 VlasakovaK.TrothS

Similarly, while it is clear that glycogen loading can increase intracellular water content [31], muscle thickness [15], and lean body mass (LBM) estimates [32], the relative extent of intracellular hydration in grams of water per gram of glycogen may vary so greatly that it is not statistically correlated with glycogen content [30]

550 Concurrently, another demethylase, FTO, through its interaction with lncRNAs adjacent to X-inactive specific transcript, facilitates the demethylation process of phosphoinositide-dependent kinase-1, which not only promotes aerobic glycolysis in glioma cells but also strengthens their resistance to temozolomide

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