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Cells exposed to TB-500 appeared to express increased levels of angiopoietin-2, the Tie2 receptor, and vascular endothelial growth factor A (VEGFA)

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The protein-binding assays are rapid, sensitive, and require no treatment of the urine sample prior to analysis

It was shown that TQ (100 nM) (1 g/ml FM1-43 for 5 min(, can have inhibitory effects against the synaptic activity, protective effects on cultured hippocampal neurons against synapse damage induced by alpha SN, and decrement effects on synaptophysin level (Elibol et al., 2019)