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Indeed, superoxide production has previously been demonstrated to be linked to the susceptibility of MNA NB cells to DPI, resulting in cytochrome c release, caspase activation, cytochrome c release and cell death (16)

[DOI] [PMC free article] [PubMed] [Google Scholar] Schinn S

Moreover, G6PD expression was positively associated with microglial activation and dopaminergic neurodegeneration (245), indicating that oxidative stress is closely linked to neurodegeneration

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While traditional methods may offer insights into culturally preferred flavors and techniques, they may not always align with modern food safety standards, quality control measures, and scientific understanding of the fermentation process [74,75,76]

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