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Comment: We received a comment in support of the increased applicable percentage of 26 percent for certain orphan drugs, which we finalized last year in the CY 2024 PFS final rule

Sarilumab (Kevzara) and tocilizumab (Actermra)

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Sections 503A and 503B of the FD&C Act allow pharmacies and registered outsourcing facilities (facilities registered with the FDA under Section 503B that may compound larger volumes of drugs without individual patient prescriptions), respectively, to compound customized medications but not copies of commercially available drugs, unless those drugs are on the FDAs shortage list (a publicly available, regularly updated database identifying drugs whose national supply cannot meet current demand)

Safety advice liver Aquaviron Injection 1ml may not be safe for individuals with liver disease and is recommended to be avoided