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Once in the liver, stores of vitamin B12 are generally large enough to supply adequate levels for over five years

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[DOI] [PubMed] [Google Scholar] 15.Banek N., Martens L., Daluege N., Carty N., Schmeier S., Trutz O., Young K.W., Bohnhorst P

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Metformin: this medication, used to treat type 2 diabetes, can reduce the absorption of vitamin b12, increasing the risk of deficiency